News

Nikita’s, Bram’s and Dani’s work on self-organization of microtubules has been published in Chaos, Solitons & Fractals

Microtubules self-organize to form part of the cellular cytoskeleton. They give cells their shape and play a crucial role in cell division and intracellular transport. Although the topic has been extensively studied, the question remains: What defines such microtubule networks’ spatial order and robustness? In their work, Nikita, Bram and Dani have investigated a simplified […]

Nikita’s, Bram’s and Dani’s work on self-organization of microtubules has been published in Chaos, Solitons & Fractals Read More »

Oral and poster presentations at the EMBL Symposium 2024 in Heidelberg, Germany

Martina, Dani and Lendert joined the EMBL Symposium on “Biological oscillators: rhythms and synchronization across scales” held in Heidelberg between the 19th and 22nd of March 2024. Martina presented her work on the influence of the cytoskeleton on cell cycle period in an oral presentation while Daniel and Lendert presented their work on wave phenomena

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Bartosz’s work on discovering biological oscillator models from data now out in iScience

Periodic changes in the concentration or activity of different molecules regulate vital cellular processes such as cell division and circadian rhythms. Developing mathematical models is essential to better understand the mechanisms underlying these oscillations. Sparse Identification of Nonlinear Dynamics (SINDy) is a method that uses data to uncover the underlying equations of dynamical systems. It

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Welcome Nicole

Welcome to our lab, Nicole! Nicole will be investigating the influence of temperature and other environmental factors on embryonic development. She will be working as joint PhD student with Prof. Luc Brendonck (KU Leuven).  

Welcome Nicole Read More »

Bartosz joins the 22nd International Conference on Systems Biology in Hartford, Connecticut, USA 

Bartosz has participated at the 22nd International Conference on Systems Biology held in Hartford, Connecticut, USA, between the 8th and 12th of October. At the conference, Bartosz gave a talk on the results of his recent preprint ‘Data-driven discovery of oscillator models using SINDy: Towards the application on experimental data in biology’ (see here). In

Bartosz joins the 22nd International Conference on Systems Biology in Hartford, Connecticut, USA  Read More »

Liliana joins the 19th International Xenopus Conference in Cambridge, Maryland, USA

Liliana joined the 19th International Xenopus Conference held in Cambridge, Maryland, USA, between the 20th and 24th of August. During the conference, Lili presented her latest experimental work with a poster on how nuclei affect cell cycle timing using an artificial cell system consisting of droplets of Xenopus frog extracts. This work was carried out

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The ups and downs of biological oscillators: a comparison of time-delayed negative feedback mechanisms

Many biochemical oscillators are driven by the periodic rise and fall of protein concentrations or activities. A negative feedback loop underlies such oscillations. The feedback can act on different parts of the biochemical network. Jan and Sarah mathematically compare time-delay models where the feedback affects production and degradation and how both mechanisms impose different constraints

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Challenges in identifying simple pattern-forming mechanisms in the development of settlements using demographic data

Rapid increase of population and settlement structures in the Global South motivate the development of suitable models to describe their formation. Such settlement formation has been previously suggested to be dynamically driven by simple pattern-forming mechanisms. In this work Bartosz and our collaborators from TU Darmstadt explored the use of a data-driven white-box approach, called

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