News

Cell cycle oscillations driven by two interlinked bistable switches

Negative feedback is at the heart of cell cycle oscillations: active cyclin B-Cdk1 activates the Anaphase-Promoting Complex-Cyclosome, which triggers the degradation of cyclin B. In the early embryos of the frog Xenopus laevis, such cell cycle oscillations occur fast and periodically. In this paper by Pedro and Dani, we built several cell cycle oscillator models […]

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Welcome Martina!

We are happy to welcome our new PhD student Martina to our lab! Martina studied biomedical engineering in Milan, Italy, where she was especially passionate about microfluidics and biosensors. In our group, she will use microfluidic approaches to study how frog egg extracts behave in different spatial and chemical environments.

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Self-organized sulfide-driven traveling pulses shape seagrass meadows

Traveling pulses of vegetation are able to form strikingly complex seascapes as Dani and his former group have shown in Posidonia oceanica meadows. They prove that these spatiotemporal structures arise due to the excitable dynamics mediated by the accumulation of sulfides in the sediment, which are toxic to the plants, on the basis of mathematical

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Lendert gives talk at Cell Bio 2022 (ASCB/EMBO Workshop) in Washington, D.C, US

Lendert joined the ASCB/EMBO Workshop ‘Cell Bio 2022’ which took place in Washington, D.C, US between the 3rd and 7th of December. During his talk, Lendert presented our recent theoretical work and discussed how the complexity of a cell cycle oscillator models can be reduced by replacing the detailed reaction mechanisms of ultrasensitive and bistable

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Bartosz and Nikita join the IB² research day in Brussels, Belgium

Nikita, Bartosz and Daniel joined the IB² research day on Bioinformatics at the Vrije Universiteit Brussels in November. Bartosz gave a talk presenting his recent work on the use of the data-driven machine learning techniques (SINDy) to identify biological oscillator models from time series. Nikita presented a poster on how cell cycle duration scales with

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Welcome Nikita

Welcome to our lab, Nikita! Nikita has investigated nonlinear dynamics, synchronization and chaotic behavior in high-energy electron flows during his thesis and has since then switched to the topic of graph theory and neuroscience. He will use his knowledge from machine Learning, statistics and nonlinear dynamics to analyze experimental data of frog egg extracts and

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